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Oregon vs Oklahoma State: Game Preview

Oregon Ducks (1-0) visit Oklahoma State (0-1) on Saturday, Sept. 12, 2026 at 12 p.m. ET from Boone Pickens Stadium.

The Ducks come off a 34-27 win over Boise State, with quarterback Dante Moore throwing for 378 yards and three touchdowns. The Cowboys, 0-1 after losing to Tulsa 24-10, will need improved play from quarterback Drew Mestemaker who threw two interceptions in their opener.

Oregon is a heavy 22.5-point favorite with a total of 57.5 points. The Ducks are favored at -2174 on the moneyline while the Cowboys sit at +1050, as they look to bounce back at home against a high-powered Oregon offense. cat-cross.com