2026 NFL Week 2 Odds Released

Week 2 NFL odds are now available, with the Lions facing the Bills in Buffalo headlining the schedule. The Bills are favored by 3.5 points with a moneyline of -185, while the Lions sit at +155. The over/under is set at 53.5 points for this Thursday night contest.

Other notable matchups include the Panthers at Falcons (Falcons -1.5), Bengals at Texans (Texans -2.5), and the Browns at Buccaneers (Bucs -8.5). The 49ers are heavy favorites (-12.5) against the Dolphins, while several games including Commanders-Cowboys and Giants-Rams still have TBD lines as of September 14. solvita.blog